The side effects of Masteron Enanthate can and primarily surround those of an androgenic nature. The androgenic side effects of Masteron Enanthate may include acne, hair loss in men predisposed to male pattern baldness and body hair growth. Despite a potent binding relationship to the androgen receptor the total androgenic activity should not be extreme and such side effects should not be extreme. If you are predisposed to male pattern baldness this steroid is well known for speeding up hair loss and should be avoided if that is a concern. If you are not predisposed hair loss is impossible.
Important Note: the 5-alpha reductase enzyme, the enzyme that reduces testosterone to DHT, does not metabolize Drostanolone. There is no reduction; it’s already DHT. Because no reduction exists there is nothing to inhibit or block and this means 5-alpha reductase inhibitors like Finasteride will do nothing to combat androgenic effects.
Masteron Enanthate can also promote virilization symptoms in women. Virilization refers to the promotion of male characteristics in women, specifically body hair growth, a deepening of the vocal chords and clitoral enlargement. It is very possible to use this steroid without these issues, although genetic sensitivity will play a role. If symptoms begin to show simply discontinue use and they will rapidly go away. It is when virilization symptoms are allowed to set in that they become a problem and in some cases irreversible.
Important note: Female users of Drostanolone will be best served by choosing Drostanolone Propionate as it will clear the body faster should issues arise.
First and foremost, it is important to mention that there is no risk what so ever of any Estrogen related side effects from Masteron Enanthate alone. As mentioned previously, Masteron Enanthate not only avoids aromatization into Estrogen completely, but it even acts as an anti-Estrogen in many cases. Therefore, the typical estrogenic side effects that result from the use of aromatizable anabolic steroids is avoided. This includes: bloating, water retention, blood pressure increases (as a result of water retention), acne, and gynecomastia. Because of Masteron’s anti-estrogenic properties, it can actually help prevent or mitigate these side effects if they are occurring from other anabolic steroids that do aromatize.
Many bodybuilders combine drostanolone with other AAS. [ citation needed ] Drostanolone itself is only weakly anabolic, which is why it is not used alone during bulking cycles. [ citation needed ] However, when combined with other anabolic steroids, drostanolone may enhance their effects. Also, drostanolone binds sex hormone-binding globulin (SHBG) which usually will bind a portion of free sex hormones and steroids, like testosterone, and inactivate them. When drostanolone binds to SHBG, the level of unbound SHBG drops, lowering the chance of it binding to other steroids, which increases their bioavailablilty.