In May 2002, Mast began feeling ill suddenly.  He had lost weight and was forced to miss races to take medical tests to find out what was wrong. It turned out that he had suffered carbon monoxide poisoning and Mast was forced to retire.  He officially retired on January 22, 2003 at age 45.  After his retirement, he spoke with NASCAR president Mike Helton about having teams redesign their air intake systems to get less exhaust fumes into drivers' helmets.  When NASCAR completely redesigned its race vehicle with the Car of Tomorrow , it changed the exhaust exit location to be away from the driver and it cited carbon monoxide poisoning cases like Mast's as a reason for the change. 
Armed with this clue, the researchers then went back through thousands of patient records for healthy people. When they looked at the DNA results of people with high tryptase levels, they found that all of them also had the TPSAB1 mutation. The scientists then interviewed a number of these supposedly hearty specimens and found that all of them were living with symptoms that sounded suspiciously similar to those of EDS-HT, POTS, and MCAS. They'd just never been diagnosed. (This is unsurprising—the average time to diagnosis for a person with EDS-HT is 10 years .)
MOTIVATED RESPONSIBLE PERSONS ARE REQUIRED TO MAINTAIN EVERYTHING EVEN PERSONAL RELATIONSHIPS. THIS IS EVEN MORE IMPORTANT IN DEVELOPING COUNTRIES BECAUSE SPARE PARTS AND EXPERIENCED SERVICE ARE NOT AS AVAILABLE. MOST AMERICAN BUSINESSES BUY USED EQUIPMENT WHENEVER THEY CAN AND MAINTAIN IT THEMSELVES ESPECIALLY WHEN THEY ARE GROWING. THE NEW EQUIPMENT IS OFTEN TOO EXPENSIVE AND STILL HAS TO BE OPERATED AND MAINTAINED PROPERLY FROM THE FIRST DAY OR THE DOWN TIME PUTS US OUT OF PROFITABLE BUSINESS. IF WE DO NOT HAVE TIME TO "DO IT RIGHT" WHEN WILL WE FIND TIME "TO DO IT OVER".