A popular legend holds that the first schooner was built by builder Andrew Robinson and launched in Gloucester, Massachusetts where a spectator exclaimed "Oh how she scoons", scoon being similar to scone ,  a Scots word meaning to skip along the surface of the water.   Robinson replied, "A schooner let her be."  The launch is variously described as being in 1713 or 1745.  Naval architects such as Howard Chapelle have dismissed this invention story as a "childish fable",  but some language scholars feel that the legend may support a Gloucester origin of the word. 
Basophils arise and mature in bone marrow. When activated, basophils degranulate to release histamine , proteoglycans (. heparin and chondroitin ), and proteolytic enzymes (. elastase and lysophospholipase ). They also secrete lipid mediators like leukotrienes ( LTD-4 ), and several cytokines . Histamine and proteoglycans are pre-stored in the cell's granules while the other secreted substances are newly generated. Each of these substances contributes to inflammation. Recent evidence suggests that basophils are an important source of the cytokine, interleukin-4 , perhaps more important than T cells . Interleukin-4 is considered one of the critical cytokines in the development of allergies and the production of IgE antibody by the immune system. There are other substances that can activate basophils to secrete which suggests that these cells have other roles in inflammation.