The EarPopper is a non-invasive device for treating conditions such as otitis media with effusion, middle ear effusion, aerotitis/barotitis and eustachian tube dysfunction, without the need for surgery or antibiotics. It delivers a constant, regulated stream of air into the nasal cavity through the nostril with a 1-oz infant nasal syringe equipped with a plastic tip. During the moment of swallowing, the air is diverted up the eustachian tube clearing and ventilating the middle ear. The EarPopper relieves the negative ear pressure allowing any accumulated fluids to drain. The Australia and New Zealand Horizon Scanning Network's assessment on "EarPopper ™ for the treatment of otitis media in children" (2007) deemed this technology as "yet to emerge"; and it does not receive approval from the Australian Therapeutic Goods Administration. The assessment noted that the evidence suggested that the EarPopper ™ may provide a safe and effective treatment option in the short-term with minimal clinical impact on health practitioners as it can be used at home; and recommended that this technology be monitored.
IgG4-related sialadenitis : This term refers to IgG4-related disease (IgG4-RD) involving any of the major salivary glands, . parotid or submandibular glands. This is often symmetrical and is usually associated with manifestations of IgG4-RD elsewhere in the body. IgG4-related sialadenitis is particularly associated with involvement of one or both of the lacrimal glands (referred to as IgG4-related dacryo-sialadenitis). Mikulicz 's disease , now considered to be a subtype of IgG4-related disease,  was a term used when (i) any two of the parotid, submandibular and lacrimal glands were persistently and symmetrically enlarged and (ii) other diseases that may mimic this presentation were excluded.