Many bodybuilders favor the use of mesterolone during dieting phases or contest preparation, when low estrogen and high androgen levels are particularly desirable. This is especially beneficial when anabolics like Winstrol®, Anavar, or Primobolan® are being used alone, as the androgenic content of these drugs is relatively low. Mesterolone can be effectively used here to adjust the androgen to estrogen ratio upwards, bringing about an increase in the hardness and density of the muscles, supporting libido and general sense of well being, and increasing the tendency to burn body fat. It is also commonly used (at a similar dosage) to prevent gynecomastia when other aromatizable steroids are being administered, often in conjunction with 10-20 mg per day of Nolvadex.
Overdosing or abuse of this drug can lead to health complications such as oily skin, acne, exacerbation of male pattern baldness, growth of body/facial hair, deepening of the voice, and menstrual irregularities. The use of Mesterolone is not recommended to patients with carcinoma of the prostate or those who are undergoing androgen therapy of any kind, including the use of Proviron. In case a dose of this drug has been missed and it is almost time for the next dose, the first dose should be ignored and the next dose should be taken at the designated time. Under no circumstances, two doses of the drug should be taken together for the dose that was missed. Medical advice should be sought without any delay and use of Proviron should be stopped immediately if side effects such as pain in liver area, headache, loss of appetite, depression, unexplained weight loss, aggression, symptoms of an enlarged prostate (change in urination), acne, or hirsutism are experienced.
The side effects of Proviron will include the suppression of natural testosterone production, but it’s not as cut and dry compared to many steroids . The use of anabolic steroids, any anabolic steroid will suppress natural production; however, the rate of suppression varies greatly from one steroid to the next. In the case of Mesterolone, the total rate of suppression can be so minimal it can be insignificant. With standard Proviron doses, which normally fall in the 50-150mg per day range, the total suppression of natural testosterone production should be minimal of relatively no concern. When the dose surpasses the 150mg mark this will create a greater level of suppression, but there is no reason for any man to need a dose greater than 150mg per day. In theory, assuming your natural testosterone levels are in the high end optimal range, the individual could implement a cycle of Proviron and a moderate suppressive steroid at a low dose such as Anavar and forgo the need of exogenous testosterone supplementation. However, the Anavar dose would need to be very low and natural levels very high. Most men will still need exogenous testosterone, especially when we consider standard anabolic steroid cycles .